脑血管病是我国三大致死疾病之一,城市脑血管病在死因顺位中居第二位,仅次于恶性肿瘤[1]。缺血性脑血管病在我国致残率、致死率相当高,近年来发病率有逐渐上升趋势,传统的给药方法见效慢,治疗效果往往不尽人意。颈动脉给药为经皮穿刺,直接将药物注入颈动脉内,利用血流将药物送 Cerebrovascular disease is one of the three major lethal diseases in China. Urban cerebrovascular disease ranks second in the cause of death rank second only to malignant tumors [1]. In our country, the morbidity and mortality of ischemic cerebrovascular disease are quite high. The incidence of ischemic cerebrovascular disease is gradually increasing in recent years. The traditional method of administration is slow and the therapeutic effect is often unsatisfactory. Carotid administration for percutaneous puncture, direct injection of drugs into the carotid artery, the use of blood flow to the drug delivery