论文部分内容阅读
目的:观察米非司酮治疗子宫肌瘤的临床效果。方法:选取本院2014年6月至2015年6月接诊的子宫肌瘤患者40例,所有患者由就诊当天开始空腹服用10mg米非司酮,连续服用2个月,经妇科检查及B超对比治疗前后子宫肌瘤的体积,对于多发肌瘤的患者,以最大肌瘤代表结果。结果:经过2个月的治疗,为患者进行妇B超及妇科检查,患者子宫及子宫肌瘤体积明显减少。总有效率为80%,不同类型肌瘤治疗效果:单发肌壁间肌瘤83.33%,多发肌瘤75%,浆膜下肌瘤75.57%。血红蛋白及血清生殖激素水平治疗前后对比差异显著(P<0.05),具有统计学,出现头晕、恶心的共5例,下腹痛的共3例,程度较轻,停药后立即消失。结论:米非司酮治疗子宫肌瘤可取得良好的临床效果,且不良反应少,是可行的保守治疗法。
Objective: To observe the clinical effect of mifepristone in treating uterine fibroids. Methods: Forty patients with uterine fibroids admitted from June 2014 to June 2015 in our hospital were enrolled in this study. All patients took 10 mg of mifepristone on an empty stomach on the day of treatment and took for 2 months continuously. After gynecological examination and B- Before and after treatment of uterine fibroids volume, for patients with multiple fibroids, the largest fibroid results. Results: After 2 months of treatment, the patients underwent gynecological ultrasound and gynecological examinations. The volume of uterine and uterine fibroids was significantly reduced. The total effective rate was 80%. The therapeutic effect of different types of fibroids: single intramural fibroids 83.33%, multiple fibroids 75%, subserosal fibroids 75.57%. Hemoglobin and serum reproductive hormone levels before and after treatment were significantly different (P <0.05), with statistics, dizziness, nausea in 5 cases, a total of 3 cases of lower abdominal pain, the degree of mild withdrawal immediately after withdrawal. Conclusion: Mifepristone treatment of uterine fibroids can achieve good clinical results, and fewer adverse reactions, is a viable conservative treatment.