不同急性淋巴细胞白血病患者的预后存在差异,部分患者会由于复发难治而失去生命,其难以根治的原因之一是体内存在白血病干细胞,而目前由于白血病细胞对对化疗药物产生耐药,严重阻碍了急性淋巴细胞白血病的治疗。随着医学技术的快速发展,靶向治疗的地位越来越重要。本文主要对该病靶向治疗的方法、机制及现状进行了综述。 The prognosis of patients with different acute lymphoblastic leukemia is different, some patients will be refractory to relapse due to the loss of life, one of the reasons it is difficult to cure the body of leukemia stem cells exist, and now due to leukemia cells on the chemotherapeutic drug resistance, a serious obstacle Acute lymphoblastic leukemia treatment. With the rapid development of medical technology, the status of targeted therapy is more and more important. This article mainly reviews the method, mechanism and current situation of targeted therapy of this disease.