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目的探讨18F-脱氧葡萄糖(FDG)PET/CT在头颈部肿瘤放射治疗中的临床应用价值。方法对78例拟执行放射治疗的头颈部恶性肿瘤患者行18F-FDGPET/CT扫描,依据PET图像、CT图像和PET/CT融合图像进行帧对帧对比分析,联合标准化摄取值(SUV)进行综合评价。结果 78例拟行放射治疗的患者中,有8例准备行根治性放射治疗的患者由于发现远处转移而改为姑息放射治疗;20例患者重新勾画了放疗生物靶区和调整了放射剂量;29例患者TNM分期发生改变。结论 18F-FDGPET/CT显像能精确勾画放疗的生物靶区,提高头颈部肿瘤的诊断、分期和定位的准确性,准确而快速地确定肿瘤复发的位置与侵犯范围,在头颈部肿瘤的放射治疗方案的制定、疗效判断及预后起着重要的作用。
Objective To investigate the clinical value of 18F-FDG PET / CT in radiotherapy of head and neck cancer. Methods Seventy-eight patients with head and neck malignant tumor undergoing radiotherapy were examined by 18F-FDG PET / CT. The frame-to-frame comparison of PET images, CT images and PET / CT images was performed with SUV Overview. Results Of the 78 patients who underwent radiotherapy, 8 patients who were scheduled for radical radiotherapy were converted to palliative radiotherapy because of distant metastases; 20 patients were redesigned to radiotherapy biological target area and radiation dose was adjusted; Twenty-nine patients had TNM staging changed. Conclusion 18F-FDG PET / CT imaging can accurately delineate the biological target area of radiotherapy, improve the accuracy of diagnosis, staging and location of head and neck cancer, accurately and quickly determine the location and extent of tumor recurrence, The development of radiation therapy programs, the efficacy of judgment and prognosis play an important role.