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The experiment was conducted to approve the efficacy of functional compound recipe liquid of eliminating lead andrncalcium to eliminate lead in rats. Total 120 rats were divided into six groups according to weight: blank group (CK), negative grouprn(ND), positive group (PD) and high group (HD, 6.67 Mg ? kg-1 ? BW ? d-1), middle group (MD, 3.33 Mg ? kg-1 ? BW ? d-1) and low group (LD,rn1.67 Mg ? kg-1 ? BW ? d-1 three groups). Except CK, other groups were drunk 0.24% Pb(AC)2, in which rats were fi lled with functionalrncompound recipe liquid to eliminate lead and DSMA was added to positive group (PD). On the 20th day, the blood was collectedrnfrom the tail. on the 40th day, the whole blood was collected from eyeball. After executed, liver and blood were collected to determinernthe content of lead and calcium. Results showed that lead contents in blood and liver of three dosage groups obviously decreasedrncompared with ND and there was signifi cant difference between any two groups of three dosage groups (P<0.01). Meanwhile, therncalcium concentration increased in three dosage groups. It is concluded that the functional compound recipe liquid of eliminating leadrnhas the evident function of eliminating lead and can promote calcium absorption.