儿童癌肿患者的治疗将改变口腔环境,使需氧革兰氏阴性菌(GNB)易于移生并致感染,产生内毒素释放至口腔中。本文目的是评价涎液内毒素水平能否检测儿童白血病患者存在感染。 材料和方法 选择12例正接受化学药物治疗的儿童白血病患者和12例与患者年龄、性别相接近的健康儿童,分别测定其口咽部需氧GNB移生情况和诞液 Treatment of pediatric cancer patients will alter the oral environment, allowing aerobic Gram-negative bacteria (GNB) to easily migrate and become infected, producing endotoxin release into the oral cavity. The purpose of this article is to evaluate whether salivary endotoxin levels can detect infections in children with leukemia. MATERIALS AND METHODS Twelve patients with childhood leukemia and 12 healthy children with similar age and sex were enrolled in this study. Aerobic GNB translocation and orodynia