本文应用IBAS图象分析——显微分光光度系统测定11例胃、结肠重度异型增生(severe dysplasia,Dys Ⅱ)和高分化腺癌(well differentiated adenoca cinoma,WDCa)细胞核的DNA含量,发现各例Dys Ⅲ及WDCa均含非整倍体细胞。同一病例自身比较表明,近半数病例的Dys Ⅲ和WDCa的DNA均值无显著差别。K-S检验结果也显示Dys Ⅲ和WDCa的DNA含量分布有半数病例为同一分布类型。本文支持异型增生属于肿瘤范畴的观点,并对Dys Ⅲ的本质进行了探讨。 In this paper, the DNA content of 11 cases of severe dysplasia (Dys II) and well differentiated adenocacinoma (WDCa) were determined by IBAS image analysis-microscopic spectrophotometry. Both Dys III and WDCa contain aneuploid cells. The comparison of the same case shows that there is no significant difference in the mean DNA of Dys III and WDCa in nearly half of the cases. K-S test results also showed that half of the DNA distributions of Dys III and WDCa were of the same distribution type. This article supports the view that dysplasia belongs to the category of tumors and discusses the nature of Dys III.