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作者研究了由一种少见、不知名、嗜盐、发酵乳糖(L~+)的弧菌引起疾病的临床和流行病学特征。39名分离到L~+弧菌的病人呈现两种明显不同的临床症状。第一种(原发性败血症型),有24例病人以典型的败血症发病:发冷,发热,衰竭。呕吐和腹泻不常见。有18例病人在发病后36个小时内,出现续发性表皮损伤,其中13例为水泡或溃疡状,9例病例发展为坏死。该型病人20例从血液中分离到L~+弧菌。18例表皮损伤者中10例自表皮损伤处分离到L~+弧菌。6例病人从上述两处均获得L~+弧菌,在一个濒死的病人,从血液、表皮损伤、脑脊液均分离到L~+弧菌。白细胞计数,15例有记录者中6例减少(<4300/mm~3)和2例增多(>10000/mm~3)。10例病人中9例血小板减少。24例病人中,18例(75%)有既往肝病史。24例中11例死亡(46%)。第二种(创伤感染型),15例病人中的14例在发病前7天内皮肤曾有创伤。12例病人表现为蜂
The authors studied the clinical and epidemiological characteristics of the disease caused by a rare, unidentified, halophilic, fermentable lactose (L ~ +) vibrio. 39 patients isolated to L ~ + Vibrio showed two distinct clinical symptoms. The first (primary sepsis type), 24 patients with the typical onset of sepsis: chills, fever, failure. Vomiting and diarrhea are uncommon. In 18 patients, within 36 hours after onset, there was persistent epidermal injury, of which 13 were blisters or ulcers and 9 developed necrosis. 20 cases of this type of patients isolated from the blood of L ~ Vibrio. In 18 cases of epidermis injury, 10 cases of L ~ + Vibrio were isolated from epidermis lesions. 6 patients obtained Vibrio L ~ + from the above two places. In a dying patient, L ~ + Vibrio was isolated from the blood, epidermis and cerebrospinal fluid. White blood cell count was decreased in 6 of 15 cases (<4300 / mm ~ 3) and in 2 cases (> 10000 / mm ~ 3). Nine of 10 patients had thrombocytopenia. Of the 24 patients, 18 (75%) had a history of previous liver disease. Eleven of the 24 patients died (46%). In the second (traumatic infection type), 14 of the 15 patients had traumatic skin lesions within 7 days prior to onset. Twelve patients showed bee