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目的:探讨高眼压近视患者行准分子激光原位角膜磨镶术的安全性、有效性和可预测性。方法:对40例(76眼)高眼压近视患者行准分子激光原位角膜磨镶矫治术,术中行10%的切削量,术后应用泰利必妥眼液滴眼,4次/d,连用1周;双氯芬酸钠眼液滴眼,4次/d,连续应用2周。随访1年以上,观察术前、术后非接触式眼压计测量值,压陷式眼压计测量值、裸眼视力、矫正视力、屈光度及眼底视杯与视盘的比值(optic cup/optic disc,C/D)及中心视野并进行比较分析。结果:手术后较手术前非接触式眼压计测量值和压陷式眼压计测量值明显下降,手术1年后裸眼视力与术前矫正视力比较差异无统计学意义(P>0.05),屈光度在±1 D以内者为84.2%,眼底C/D未见异常,中心视野检查未见青光眼视野改变。结论:中央角膜厚度与非接触式眼压计测量值、压陷式眼压计测量值呈正相关,高眼压近视患者在密切观察视乳头及视野改变的前提下行准分子激光原位角膜磨镶术是安全、有效的。
Objective: To investigate the safety, efficacy and predictability of excimer laser in situ keratomileusis in patients with ocular hypertension. Methods: Forty cases (76 eyes) of high myopia with high intraocular pressure were treated by laser in situ keratomileusis. The patients underwent 10% Once a week; diclofenac sodium eye drops, 4 times / d, continuous application of 2 weeks. The patients were followed up for more than 1 year. The preoperative and postoperative non-contact tonometer measurements, subsidence tonometer measurements, uncorrected visual acuity, corrected visual acuity, refractive power, and ratio of optic cup / optic disc , C / D) and center of vision and comparative analysis. Results: Compared with preoperative non-contact tonometer and invagination tonometer, the measured value decreased significantly after operation. There was no significant difference between uncorrected visual acuity and preoperative corrected visual acuity (P> 0.05) Refractive index within ± 1 D were 84.2%, fundus C / D no abnormalities, central field examination showed no change in glaucoma field of vision. Conclusions: Central corneal thickness is positively correlated with non-contact tonometer and subsidence tonometer, while patients with high myopia and high myopia underwent near-field laser in situ keratomileusis Surgery is safe and effective.