患儿男,1月26 d,主因间断皮肤黄染1个半月入院。患儿系第1胎第1产,足月顺产,出生体重3400 g,生后9 d现皮肤黄染,当地医院查血生化提示肝脏损害,TORCH抗体均阴性,乙肝两对半阴性,腹部B超和MRI提示肝脾肿大、肝实质内多发结节,为进一步诊治转入我院。入院时体重5320 g,全身皮肤暗黄色,背部有1个2 cm×1cm暗红色血管瘤,肝肋下3 cm,质韧,脾肋下1cm,神经系统无 Male children, January 26 d, mainly due to intermittent skin yellow dye 1 and a half months admitted. The first fetus of children with first birth, full-term birth, birth weight 3400 g, 9 days after birth, the skin is yellow dye, local hospital biochemical examination showed liver damage, TORCH antibodies were negative, hepatitis B two pairs of semi-negative, abdomen B Super and MRI prompted hepatosplenomegaly, multiple nodules within the liver parenchyma, transferred to our hospital for further diagnosis and treatment. Admission weight 5320 g, body dark yellow skin, the back of a 2 cm × 1cm dark red hemangioma, liver ribs 3 cm, quality tough, spleen ribs 1cm, the nervous system without