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目的探讨采用不同的辅助化疗方法对局部宫颈癌的临床治疗效果。方法实验对象选自我院2016年2月~2017年1月收治的宫颈癌患者86例。随机将其分为实验组和对照组,两组化疗方案不同。其中实验组为动脉介入,先实施术前化疗即子宫双侧动脉介入并栓塞,然后使用紫杉醇联合卡铂进行新辅助化疗;对照组采用静脉用药,经外周静脉置入中心静脉导管实施术前化疗,然后使用伊立替康联合卡铂进行新辅助化疗。结果实验组和对照组的临床治疗结果无明显差异,不良反应也无明显差异,P>0.05。结论不同的辅助化疗方案对局部宫颈癌具有不同的治疗效果,应根据患者病情采用最适合的方案。
Objective To investigate the clinical effect of different adjuvant chemotherapy on local cervical cancer. Methods The subjects were selected from 86 patients with cervical cancer who were admitted to our hospital from February 2016 to January 2017. Randomly divided into experimental group and control group, two chemotherapy regimens are different. The experimental group for arterial intervention, the first implementation of preoperative chemotherapy that uterine arterial intervention and embolization, and then the use of paclitaxel combined carboplatin neoadjuvant chemotherapy; control group with intravenous drug, peripheral vein catheterization of the implementation of preoperative chemotherapy , Followed by irinotecan plus carboplatin for neoadjuvant chemotherapy. Results There was no significant difference in clinical treatment between the experimental group and the control group, with no significant difference in adverse reactions (P> 0.05). Conclusion Different adjuvant chemotherapy regimens have different therapeutic effects on local cervical cancer. The most suitable regimen should be adopted according to the patient’s condition.