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1959～1984年收治小儿遗传性球形细胞增多症20例,男12例,女8例。年龄最小3个月,最大11岁。均有黄疸、贫血、肝肿大及明显脾肿大。诊断中,提出用位相显微镜更易发现球形红细胞,自身溶血试验及葡萄糖纠正可提高本症诊断率。并应注意与传染性肝炎、疟疾、地中海贫血、新生儿溶血症相鉴别。确诊后即使轻型均应作脾切除,2～4岁后施行较宜。骨髓中出现类巨中,晚幼红细胞,加用叶酸、维生素B_(12)治疗。
From 1959 to 1984 admitted to children with hereditary spherocytosis in 20 cases, 12 males and 8 females. The youngest 3 months, maximum 11 years old. Have jaundice, anemia, hepatomegaly and obvious splenomegaly. Diagnosis, the proposed phase microscope easier to find spherical red blood cells, hemolytic test and glucose correction can improve the diagnosis of this disease. And should pay attention to infectious hepatitis, malaria, thalassemia, neonatal hemolytic phase phase identification. Even after diagnosis of light should be splenectomy, 2 to 4 years after the implementation of the appropriate. Bone marrow appears in the class giant late red blood cells, plus folic acid, vitamin B_ (12) treatment.