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The authors studied the effect of transcranial ultrasound on patients with acu te middle cerebral artery occlusion and contraindications for thrombolysis. Fift een consecutive subjects were randomized for insonation over 1 hour or for inclusion in a control group. By day 4, recanalization and neurologic improvem ent occurred more frequently in the target group. Ultrasound-induced accelerati on of clot dissolution may be an option for patients with contraindications for recombinant tissue plasminogen activator.
The authors studied the effect of transcranial ultrasound on patients with acu te middle cerebral artery occlusion and contra indications for thrombolysis. Fift een consecutive subjects were randomized for insonation over 1 hour or for inclusion in a control group. By day 4, recanalization and neurologic improvem ent occurred more frequently in the target group. Ultrasound-induced accelerati on of clot dissolution may be an option for patients with contraindications for recombinant tissue plasminogen activator.