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目的:探讨血清降钙素原(PCT)在儿科感染中的临床价值。方法:选取本院2012年4月-2014年12月收治的疑似感染性疾病患儿115例,诊断后分为细菌感染组64例、非细菌感染组51例,另选取同期正常儿童35例为对照组,检测以上儿童PCT、白细胞计数(WBC)及C反应蛋白(CRP)水平。结果:细菌感染组患儿及非细菌感染组患儿WBC及CRP检测值均明显高于对照组(P<0.05);细菌感染组患者PCT高于对照组(P<0.05),非细菌感染组患者PCT同对照组比较,差异无统计学意义(P>0.05);且细菌感染组患儿PCT、WBC及CRP水平高于非细菌感染组患儿,组间比较,差异具有统计学意义(P<0.05)。细菌感染组患儿PCT阳性率为79.69%,非细菌感染组患儿PCT阳性率为13.73%(P<0.05)。结论:PCT可作为儿科感染的治疗效果及严重程度的评价指标,且对临床中抗生素的合理使用具有一定指导价值。
Objective: To investigate the clinical value of serum procalcitonin (PCT) in pediatric infection. Methods: A total of 115 children with suspected infectious diseases admitted from April 2012 to December 2014 in our hospital were selected and divided into 64 cases of bacterial infection, 51 cases of non-bacterial infection and 35 cases of normal children In the control group, the PCT, WBC and C-reactive protein (CRP) levels of the above children were detected. Results: The values of WBC and CRP in bacterial infection group and non-bacterial infection group were significantly higher than those in control group (P <0.05). PCT in bacterial infection group was higher than that in control group (P <0.05) There was no significant difference in PCT between the two groups (P> 0.05). The levels of PCT, WBC and CRP in children with bacterial infection were significantly higher than those in non-bacterial infection group (P> 0.05) <0.05). The positive rate of PCT in children with bacterial infection was 79.69%. The positive rate of PCT in children with bacterial infection was 13.73% (P <0.05). Conclusion: PCT can be used as an evaluation index for the treatment effect and severity of pediatric infection, and it is of guiding value to the rational use of antibiotics in clinic.