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据报道低镁血症与心律失常,冠心病猝死和急性心肌梗塞(AMI)的死亡率增高有密切相关。为探讨镁剂对AMI的疗效,作者晚近将103例AMI住院患者,随机分为硫酸镁治疗(50例)和安慰剂组(5例),进行了双盲对照研究、观察、记录了心律失常,充血性心衰的发生率及院内死亡率。两组在年龄、性别,胸痛开始的平均时间和流行病学危险因素等方面无显著差异。治疗组在入院的48小时内给予硫酸镁22克(91.6毫摩),溶于等渗葡萄糖液500毫升内静脉滴注。给药方法:前3小时6克,后21小时10
It is reported that hypomagnesemia is closely related to the increase of arrhythmia, sudden death of coronary heart disease and acute myocardial infarction (AMI). To investigate the efficacy of magnesium on AMI, 103 recent AMI inpatients were randomly divided into magnesium sulfate (n = 50) and placebo (n = 5). A double-blind controlled study was performed to observe and record arrhythmia , The incidence of congestive heart failure and hospital mortality. There was no significant difference between the two groups in terms of age, sex, mean time to onset of chest pain, and epidemiological risk factors. The treatment group was given 22 grams (91.6 millimoles) of magnesium sulfate within 48 hours of admission, dissolved in 500 ml of isotonic glucose solution intravenously. Method of administration: 6 grams in the first 3 hours and 21 hours after the 10