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目的:调查我院各临床科室抗菌药物使用情况,对不合理用药情况进行分析,为临床合理使用抗菌药物提供参考.方法:从我院2011年7月至2013年6月的归档病历中,每月抽取100份出院病历,涉及各临床科室,对使用抗菌药物的病历进行统计分析,内容包括病原学检查、抗菌药物品种、抗菌药物使用率及使用强度、不合理用药情况等.结果:我院微生物检验样本送检率为54.71%;第三代头孢菌素(头孢他啶)在头孢菌素类药物中使用频次最高;Ⅰ类手术预防使用抗菌药物比例偏高;不合理用药情况时有发生,包括选药不当、用量过大、使用级别过高、联合用药不合理等.结论:我院不合理用药情况时有发生,临床药师应加大对临床用药的干预力度,避免抗菌药物滥用,减少细菌耐药,减轻病人负担.“,”Objective:To investigate the use of inpatients' antibiotics,to analysis the irrational drug used,and to provide reasonable reference for clinical rational drug use.Methods:A total of 2 400 medical records from July 2011 to June 2013 were analyzed including all various clinical departments.These medical records which had used antibiotics were analyzed.The variety of antibiotics,utilization rate of antibiotics,Defined Daily Dose,irrational drug use and so on are included.Results:The submission rate of microbiological testing samples was 54.71%.The use of third-generation cephalosporins (ceftazidime) was the most frequent.The proportion of prophylactic antibiotics for Type Ⅰ incision operation was high.Irrational usage of antibiotics still existed including the selection of unreasonable drug use,the use of excessive doses and high levels,joint use of drugs and so on.Conclusions:Irrational usage of antibiotics still existed in our hospital and need to be regulated.