哮喘患儿长期应用氨茶碱后血浆脂蛋白水平的研究

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本文对28例长期应用氨茶碱的哮喘患儿血浆脂蛋白水平进行检测,结果报告如下:1. 临床资料1.1 对象选择年龄6~14岁(平均年龄8.2岁),有两年以上哮喘病史的患儿,男女各半,将其分为两组.A组28例,接受氨茶碱口服治疗至少3个月,B组3个月内未用茶碱类药物治疗.两组病人在就诊时均先静滴或口服氨茶碱控制急性哮喘症状.剔除使用肾上腺皮质激素及接受抗菌素治疗者.另外选择无哮喘病史的健康儿童作对照组(C组),年龄5~14岁(平均年龄7.8岁,男女各半).所有对象均无哮喘之外的急慢性病,双亲中末患有心血管病、内分泌疾病、肾脏病史及高脂血症。1.2 方法受试者均空腹采血。测血糖水平;采用美国Technican公司生产的RA-1000生化分析仪检测血浆脂蛋白含量。以差异分析和均数的t检验计算各组间的统计学意义。2.结果3组儿童空腹血糖水平均在正常范围(3.4~5.6mmol/L).血浆甘油三脂(TG)、总胆固醇(Tch)、 In this paper, 28 cases of long-term use of aminophylline in children with asthma plasma lipoprotein levels were detected, the results reported as follows: 1.Clinical data 1.1 Object Selection age 6 to 14 years (mean age 8.2 years), with more than two years of history of asthma Children, male and female half, divided into two groups.A group of 28 patients, taking aminophylline oral treatment of at least 3 months, B group within 3 months without theophylline treatment .Two groups of patients at the time of treatment The first intravenous or oral aminophylline control of acute asthma symptoms, excluding the use of adrenal cortex hormones and antibiotics were also selected healthy children without a history of asthma as a control group (C group), aged 5 to 14 years (mean age 7.8 Year old, half male and half female) .All subjects had no acute and chronic diseases other than asthma, and their parents had cardiovascular disease, endocrine disease, renal history and hyperlipidemia. 1.2 Methods The subjects were fasting blood. The blood glucose level was measured. The plasma lipoprotein level was measured by the RA-1000 biochemical analyzer manufactured by Technican Company of USA. Statistical analysis of each group was performed using t-test of variance analysis and mean. Results The fasting blood glucose levels of all three groups were in the normal range (3.4-5.6 mmol / L) .TG, Tch,
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