本文根据多年对低比转数高速复合叶轮离心泵的设计和实践，建立了其性能预测的数学模型，并在该模型的基础上提出了以效率为目标函数、以抗汽蚀性能和工作稳定性为约束条件的优化设计方法，对两台比转数为２１和４３的高速复合叶轮离心泵进行了试验验证，表明了本文提出的性能预测模型和优化设计方法是合理可行的． According to the design and practice of high speed low speed compound impeller centrifugal pump for many years, this paper established a mathematical model of its performance prediction. Based on the model, the efficiency as the objective function, the anti-cavitation performance and working stability The optimization design method of the constraint condition is used to test two high-speed composite impeller centrifugal pumps with revs of 21 and 43, which shows that the performance prediction model and the optimization design method proposed in this paper are reasonable and feasible.