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近年来研究表明,遗传因素在系统性红斑狼疮(ＳＬＥ)的发病中起着重要的作用。ＳＬＥ在某些种族人群中的发病率明显高于其他种族,狼疮发病具有家庭聚集倾向,10%～12%的有1位或1位以上的一级亲属发病,同卵双生子ＳＬＥ发病的一致率(25%～70%)明显高于异卵双生子(2%～9%)。ＨＬＡ?
In recent years, studies have shown that genetic factors play an important role in the pathogenesis of systemic lupus erythematosus (SLE). The prevalence of SLE in some ethnic groups is significantly higher than that in other races. The incidence of lupus has familial aggregation tendency. The incidence of SLE in identical twins is 10% to 12% with first-degree relatives of 1 or more Rates (25% -70%) were significantly higher than those of fraternal twins (2% -9%). HLA?