【摘 要】
：
目的 观察连续2个周期大剂量地塞米松对成人新诊断的原发免疫性血小板减少症(ITP)患者的疗效及安全性.方法 将59例新诊断的ITP患者随机分为两组,地塞米松治疗组30例,地塞米松
论文部分内容阅读
目的 观察连续2个周期大剂量地塞米松对成人新诊断的原发免疫性血小板减少症(ITP)患者的疗效及安全性.方法 将59例新诊断的ITP患者随机分为两组,地塞米松治疗组30例,地塞米松40 mg/d,连用4 d,7 d后再重复1个周期,以后不进行维持治疗;泼尼松治疗组29例,1.0～1.5 mg·kg-1·d-1口服,连用4周后逐渐减量.观察二组间的近、远期疗效和安全性.结果 近期疗效:治疗后第1、2周地塞米松组有效率明显高于泼尼松组(50.0%比24.1%,73.3%比55.2%,P值分别＜0.01和0.05),治疗后第3周有效率仍高于泼尼松组,但差异无统计学意义(83.3%比68.9%,P＞0.05).远期疗效:随访3个月,除第1个月地塞米松组复发率与泼尼松组差异无统计学意义(16.0%比20.0%,P＞0.05),第2、3个月地塞米松组复发率均明显低于泼尼松组(24.0%比40.0%,32.0%比65.0%,P值分别＜0.05和0.01).地塞米松组不良反应轻微,无1例并发感染及出现库欣综合征.结论 大剂量地塞米松治疗ITP的近、远期疗效均优于常规制量泼尼松且安全性好.
其他文献
Clay-solidified grouting curtains are commonly used for remediation by containment or pollution prevention, in addition to their use as a barrier to water flow
The influence of coal desulfurization by fungus was experimentally studied. The results suggest that fungus can effectively remove inorganic and organic sulfur
Some important developments of residual stress researches for coating-based systems were studied. The following topics were included the sources of residual str
目的观察缺血后处理对肢体缺血-再灌注大鼠小肠损伤的保护作用。方法雄性Wistar大鼠108只随机均分为双后肢缺血-再灌注组(LIR组)、缺血后处理组(IPo组)和假手术组(S组)。检测
A design method for controllers and a comprehensive stability analysis for an acrobat based on Lyapunov functions are presented. Three control laws based on thr
The mechanism of particle swarm optimization algorithm is studied, and one can draw the conclusion that the best particle found by the swarm falling into local
The fatigue behaviors of 48MnV steel, both uncoated and coated with different thicknesses of 3Cr13 deposits using twin arc spraying, were investigated. The fati
目的 探讨急性髓系白血病(AML)患者TET2基因突变的发生率,并探讨其临床意义.方法 采用基因组DNA-PCR方法扩增TET2基因3～11号外显子,基因测序分析TET2基因突变,随访患者判定其
党的十八大提出多渠道增加居民财产性收入,并到2020年人均收入比2010年翻一番,但是目前我国居民财产性收入比重较低,且财产存量在居民之间具有较大差距,因此仅仅增加居民财产
The cathodic process of cerium(Ⅲ) ions in NaCl-2CsCl melt was studied by cyclic voltammetry and square wave voltammetry with tungsten and gold electrodes at 87