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探讨中国天津地区汉族人群白细胞介素4(IL-4)基因启动子区-590多态性分布特点及其与Graves病(GD)甲亢发病易感性的关系。结果表明中国天津地区汉族人与不同种族和地区人群的IL-4 (-590)基因多态性分布差异有统计学意义；在天津汉族人群中,GD甲亢与IL-4(-590)基因多态性无相关性。
To investigate the polymorphism distribution of IL-4 gene promoter -590 polymorphism and its relationship with susceptibility to Graves’ disease (GD) in Chinese Han population of Tianjin. The results showed that there were significant differences in the distribution of IL-4 (-590) gene polymorphism between Han nationality and ethnic groups in Tianjin area of China. Among the Han population of Tianjin, GD hyperthyroidism and IL-4 (-590) No relevant status.