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一.强心甙治疗心衰的原理是什么? 答:强心甙治疗心衰的药理基础主要是加强心肌收缩力,间接地减慢心率和利尿。由于收缩力加强,收缩敏捷,使心缩期缩短,舒张期相对延长。收缩力加强可使心脏排空充分,既增加心输血量,改善全身血液供应,又使衰竭扩大了的心脏容积缩小,心室舒张末期压力降低。舒张期延长有利于衰竭心脏获得较长时间休息和冠脉供血,以便更好地收缩,又有利于静脉血回流入心,使心室充盈更充分和降低静脉
A cardiac glycosides treatment of heart failure What is the principle? A: Cardiac glycosides in the treatment of heart failure is mainly based on the pharmacological effects of myocardial contractility, heart rate and diuretic indirectly reduce. Due to strengthening contractility, rapid deflation, systolic shortening, diastolic relatively prolonged. Enhanced contractility can make the heart full of empty, not only increase the blood volume of blood transfusion to improve the body’s blood supply, but also to expand the failure of the heart volume reduced, reduced ventricular end-diastolic pressure. Extended diastole is conducive to failure of the heart to obtain a longer rest and coronary blood supply in order to better contraction, but also conducive to venous return into the heart, the ventricular filling more fully and reduce the veins