论文部分内容阅读
原发性心肌病的病因至今未明,一般认为可能是多种病因综合作用的结果。现就主要有关因素作一概述: 1.病毒感染:一般认为许多病因不明的心肌炎可能是由于病毒感染所引起,有些可能是隐性病毒感染不为临床所察觉,其中病毒包括脊髓灰白质炎病毒、柯萨奇A及B病毒、ECHO病毒等肠道病毒和某些疱疹病毒、肝炎病毒等。有人报告12例原发性心肌病患者中5例(42％)有血清学证据,表示最近有柯萨奇B病毒感染。Kawai氏指出,心肌病病人与对照组相比,血清中柯萨奇B及单纯疱疹病毒补体结合抗体1:16或以上,柯萨奇B_1中和抗体1:16以上,柯萨奇B_3病毒中和抗体1:32以上者较多。这些研究提示在心肌病病人,有较高的以
The etiology of primary cardiomyopathy is still unknown, the general view may be the result of a variety of etiologies. Now the main factors to make a brief overview: 1. Viral Infection: It is generally believed that many unexplained myocarditis may be caused due to viral infection, some may be recessive virus infection is not clinically aware, including viruses, including poliovirus , Coxsackie A and B virus, ECHO virus and other enteroviruses and some herpes virus, hepatitis virus. It was reported in 5 (42%) of 12 patients with primary cardiomyopathy with serological evidence of recent Coxsackie B virus infection. Kawai’s pointed out that patients with cardiomyopathy compared with the control group, the serum Coxsackie B and herpes simplex virus complement fixation antibody 1:16 or more, Coxsackie B 1 neutralizing antibody 1:16 above, Coxsackie B_3 virus And antibodies more than 1:32 more. These studies suggest that in patients with cardiomyopathy, there is higher