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国内文献上,自孙鸿泉(1959)首次采用经鼻前孔行中隔粘膜下切除术、暴露蝶窦前壁、凿开蝶窦前及后壁(即蝶鞍前壁),成功地切除一例脑垂体嫌色细胞瘤以来,经鼻术式已日益广泛地为广大的耳鼻喉科和神经外科医师所采用。我院自1983年以来已为8例患者施行此类手术,并取得了较满意的疗效。临床资料患者男、女性各4例,年龄28岁～51岁,其中6例患有肢端肥大症,全部患者均经术后病理诊断证实,计嗜酸细胞性腺癌5例,嫌色细胞性腺癌3例。病程4月余至17年。仅2例在1年以内。
Domestic literature, since Sun Hongquan (1959) for the first time through the anterior nasolabial septum submucosal resection, the anterior sphenoidis exposure, chisel anterior and posterior sphenoid anterior wall (ie, sellae anterior wall), the successful removal of a brain Pituitary chromophoblastic tumors, nasal surgery has been increasingly widely used by the majority of otolaryngology and neurosurgeons. In our hospital since 1983, 8 patients have been such operation, and achieved more satisfactory results. Clinical data Patient male and female 4 cases, aged 28 years old to 51 years old, of which 6 cases of acromegaly, all patients confirmed by postoperative pathology, including 5 cases of eosinophilic adenocarcinoma, chromophobe gonads 3 cases of cancer. Duration of more than four months to 17 years. Only 2 cases in less than 1 year.