系统性红斑狼疮(systemiclupuserythematosus,SLE)是自身免疫病的原型,发病与遗传、性激素、感染、理化因素有关。其免疫学异常表型复杂多样,包括组织相容性抗原Ⅱ、Ⅲ,细胞因子及其受体,免疫球蛋白、T细胞抗原受体、抗原递呈细胞,自身反应性T、B淋巴细胞功能的紊乱。因病因与 Systemic lupus erythematosus (systemic lupus erythematosus, SLE) is a prototype of autoimmune diseases, the incidence and genetic, sex hormones, infections, physical and chemical factors. The immunological abnormal phenotype is complex and diverse, including histocompatibility antigens Ⅱ, Ⅲ, cytokines and their receptors, immunoglobulin, T cell antigen receptors, antigen presenting cells, autoreactive T, B lymphocyte function The disorder. Due to etiology and