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近 1 0年来 ,对一氧化氮吸入 (inhalednitricoxide ,iNO)疗法的实验和临床研究证实 ,iNO治疗新生儿持续性肺动脉高压 (PPHN)具有显效快、非创伤性、高选择性等特点 ,可明显改善部分PPHN患儿的氧合情况 ,降低肺动脉压力 ,减少体外膜肺的应用 ,但同时也存在一定的副作用。本文就iNO治疗PPHN的研究进展作一综述
In the past 10 years, experimental and clinical studies on inhaled nitric oxide (iNO) therapy have demonstrated that iNO can be used to treat persistent pulmonary hypertension (PPHN) in neonates with markedly rapid, noninvasive and highly selective characteristics To improve the oxygenation of some PPHN children, reduce pulmonary artery pressure, reduce the application of extracorporeal membrane lungs, but there are also some side effects. This article reviews the progress of iNO treatment of PPHN