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目的分析糖尿病足病治疗中前列地尔的应用疗效。方法选取2016年2月—2017年2月收治的82例糖尿病足病患者为研究对象,采用随机数字表法分为两组,给予对照组患者常规治疗法治疗,在对照组基础上给予观察组患者前列地尔治疗,对比两组临床疗效。结果观察组的临床治疗总有效率为97.56%,显著高于对照组的75.61%,差异有统计学意义(P<0.05);相对于治疗前,两组患者治疗后尿微量白蛋白、空腹血糖水平均在不同程度上降低,并且观察组显著优于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的胫神经传导速度、足背动脉峰流速均提高,与治疗前对比,差异有统计学意义(P<0.05)。结论糖尿病足病治疗中前列地尔的应用疗效显著,在临床上值得广泛推广。
Objective To analyze the therapeutic effect of alprostadil in the treatment of diabetic foot disease. Methods Totally 82 diabetic foot patients were selected from February 2016 to February 2017. The patients were divided into two groups according to the random number table. The patients in the control group were treated with conventional therapy. The patients in the control group were given the observation group Patients with alprostadil treatment, compared the clinical efficacy of two groups. Results The total effective rate of clinical observation in observation group was 97.56%, which was significantly higher than that in control group (75.61%), the difference was statistically significant (P <0.05). Compared with before treatment, urinary albumin, fasting blood glucose (P <0.05). After treatment, the tibial nerve conduction velocity and the peak dorsal flow velocity of the dorsalis pedis artery in the observation group were significantly increased, which were significantly lower than those in the control group Before comparison, the difference was statistically significant (P <0.05). Conclusion The treatment of diabetic foot disease in the application of alprostadil significant effect, it is widely worthy of clinical promotion.