药物是预防、治疗疾病的特殊物质。既有促进健康的正面效应-疗效,也有妨碍健康的负面效应-不良反应。我国的法律法规对医疗机构开展药物不良反应监测和报告工作提出了明确的要求。文章结合多年工作实践,从医疗机构开展药品不良反应监测工作的必要性和医、药、护各级人员应各尽其责,履行其应尽的义务等方面进行了初步探讨。 Drugs are special substances that prevent and cure diseases. There are both positive and negative effects of health promotion - adverse effects. The laws and regulations of our country set clear requirements for medical institutions to carry out the monitoring and reporting of adverse drug reactions. Combining with many years’ practice, this article makes a preliminary study on the necessity of monitoring adverse drug reactions in medical institutions and the efforts of doctors, pharmacists and drug officers at all levels to fulfill their due obligations.