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目的探讨影响TSGF参考值范围的因素。方法采用TSGF快速诊断试剂盒,对1886例普通体检者和53例常见患者进行筛查。常见疾病患者为一组,体检者按性别分为3个年龄段小组(20～40岁组、41～60岁组、≥61岁组)。结果同性别的不同年龄段组之间存在差异,以20～40岁组与≥61岁组的比较具有显著差异(男性Q值=4.56,女性Q值=11.65)。同年龄段组不同性别之间也有差异,20～40岁组(男:女)u值=3.353(P<0.01),≥61岁组(女:男)u值=3.246(P<0.01)。不分性别的不同年龄段组之间存在明显差异,20～40岁组与41～60岁组之间有明显差异(Q值=3.46),41～60岁组与≥61岁组之间的差异较前组明显(Q值=7.57),20～40岁组与≥61岁组之间差异最显著(Q值=10.70)。常见疾病组阳性检出率为26.42%,体检组阳性率为5.09%,两组之间有显著性差异(P<0.05)。讨论在普通体检者中,年龄的增长,导致个体差异的加大是直接影响TSGF值的参考范围大小的主要因素,性别之间也存在一定的差异,多种常见疾病可一过性增高,对大于64U/ml者仍需追踪检测。
Objective To explore the factors affecting the range of reference value of TSGF. Methods The TSGF rapid diagnostic kit was used to screen 1886 cases of general physical examination and 53 common cases. Patients with common diseases were a group. Physical examinations were divided into groups of 3 age groups according to gender (20 to 40 years old, 41 to 60 years old, and ≥ 61 years old). Results There were differences between groups of different ages in the same gender, with significant differences between the 20- to 40-year-old group and the ≥ 61-year-old group (Q=4.56 for men, Q==11.65 for women). There were also differences between genders in the same age group. The u value of the 20- to 40-year-old group (male: female) was 3.353 (P<0.01), and the u-value of the 61-year-old group (female:male) was 3.246 (P<0.01). There were significant differences between groups of different ages regardless of gender, with significant differences between the ages of 20 to 40 and 41 to 60 years old (Q value = 3.46), between 41 to 60 years old and ≥ 61 years old. The difference was more significant in the former group (Q value = 7.57), and the difference was most significant between the 20- to 40-year-old group and the ≥ 61-year-old group (Q value = 10.70). The positive rate of the common disease group was 26.42%, and the positive rate of the physical examination group was 5.09%. There was a significant difference between the two groups (P<0.05). Discussion In the general physical examination, the increase in age, leading to an increase in individual differences is the main factor directly affect the size of the reference range of TSGF value, there are also certain differences between the gender, a variety of common diseases can be transiently increased, More than 64U/ml still need to follow the test.