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哮喘是以多种炎性基因过度表达或异常表达为特征的慢性炎症。这些炎性基因包括细胞因子基因 [白细胞介素 4(ＩＬ 4 )、5、13、粒 巨噬细胞集落刺激因子 (ＧＭ ＣＳＦ) ]、炎性酶基因 [诱生型一氧化氮合酶 (ｉＮＯＳ)、环氧合酶 (ＣＯＸ 2 ) ]、趋化因子基因 [嗜酸细胞活化因子
Asthma is a chronic inflammation characterized by overexpression or aberrant expression of multiple inflammatory genes. These inflammatory genes include cytokine genes [interleukin 4 (IL 4), 5,13, granulocyte macrophage colony-stimulating factor (GM CSF)], inflammatory enzyme gene [inositol-1-inducible nitric oxide synthase ), Cyclooxygenase (COX 2)], chemokine genes [eosinophil activation factor