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目的通过检测糖尿病患者尿mAlb、β2-MG,尿中微量蛋白mAlb、β2-MG在糖尿病早期肾损害中的诊断价值。方法用放免法检测97例糖尿病患者尿mAlb、β2-MG水平,并与50例健康体检者进行对照。结果糖尿病患者尿mAlb、β2-MG明显高于对照组,差异有统计学意义(P<0.05)。结论检测尿中微量蛋白mAlb、β2-MG有助于早期诊断糖尿病患者肾损害并判定其程度,具有重要的临床意义。
Objective To evaluate the diagnostic value of urine mAlb, β2-MG, microglobulin mAlb, β2-MG in diabetic patients with early renal damage. Methods The urine mAlb and β2-MG levels in 97 diabetic patients were detected by radioimmunoassay and compared with 50 healthy controls. Results The urinary mAlb and β2-MG of diabetics were significantly higher than that of the control group (P <0.05). Conclusion Detection of microalbumin mAlb and β2-MG in urine is helpful for the early diagnosis of renal damage in diabetic patients and the determination of its extent, which has important clinical significance.