In recent years, the IT industry in China has developed rapidly and made remarkable achievements. However, there is still a big gap between China and foreign countries in the core fields of information technology, such as system hardware and software platform. Currently, foreign countries have gradually raised the restrictions of information technology in China, and even added many domestic enterprises to the restricted list, which has rung the alarm to the information security of the country. Therefore, in order to break through the foreign technology blockade and find a unique way in independent software and hardware platform, it is urgent to carry out the curriculum construction and talent training mechanism on core software and hardware platform. HarmonyOS is a “future-oriented” distributed operating system developed by Huawei. It proposes a distributed concept based on the same system capability and adapts to a variety of terminal forms, and supports a variety of terminal devices such as mobile phones, watches and smart screens. Our course on HarmonyOS aims to increase the theoretical knowledge of the core independent software and hardware platform. In the course, we exploit our teaching reform experience in the course of “Mobile Application Development”, and investigate the teaching mechanism of HarmonyOS to contribute to the rapid development of information technology and ecological construction in China.