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目的观察米非司酮配伍米索前列醇在中期妊娠引产中的作用。方法对120例10～14周妊娠的健康孕妇,要求终止妊娠孕妇分别服用米非司酮第1天50mg,2次/d,8:00,20:00。第2天8:00服50mg,第3天8:00空腹服米索前列醇0·6mg。结果完全流产占82.39%,不完全流产17·7%,成功率达94·19%,失败者占5·83%。完全流产者出血量少,未行清宫者出血时间长;不全流产者出血多,需急诊清宫,清宫后出血时间缩短。失败或不全流产清宫时操作容易,患者痛苦小且副反应少。结论米非司酮配伍米索前列酮用于终止10～14周妊娠疗效好,不良反应少,使用简便,成功率高,患者痛苦小,值得临床推广。
Objective To observe the effect of mifepristone combined with misoprostol in induction of labor during the second trimester pregnancy. Methods A total of 120 healthy pregnant women aged 10-14 weeks were enrolled in this study. Pregnant women were asked to take 50 mg, 2 d, 8:00 and 20:00 daily of mifepristone on the first day. On the second day 8:00 served 50mg, on the 3rd day 8:00 fasting misoprostol 0.6 mg. Results Total abortion accounted for 82.39%, incomplete abortion 17.7%, the success rate of 94.19%, losers accounted for 5.83%. Complete abortion less bleeding, bleeding did not line a long time; incomplete abortion bleeding, the need for emergency curettage, bleeding time after the Qing court shortened. Failure or incomplete abortion Qing operation easy, patients with less pain and fewer side effects. Conclusion Mifepristone combined with misoprostone is effective in terminating 10-14 weeks gestation, less adverse reactions, simple and convenient operation, high success rate, little pain and worthy of clinical promotion.