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红毛五加皮为五加科植物红毛五加(Acanthopanax giralolii Harms)的茎皮,为我省常用中药,具有祛风湿,通关节,强筋骨的功效,临床用于治疗痿痹,拘挛疼痛,风寒湿痹,脚膝无力,皮肤风湿及阴痿囊湿等症。尚未见药理研究报导,现将我们的研究简介于下: 一、对中枢神经系统的抑制作用 1、对戊巴比妥钠睡眠时间的影响:给药组小鼠分别灌胃红毛五加皮醇浸膏水溶液15、15和20g/kg(以原生药计算,下同)。对照组灌胃等量的生理盐水、40′后各鼠均腹腔注
Acanthopanax chinensis is the bark of the Acanthopanax giralolii Harms, which is commonly used in our province. It has the effects of removing rheumatism, joints, and bones. It is used clinically to treat paralysis and relieve pain. , Cold dampness, weakness in the legs and knees, rheumatism in the skin, and dampness in the hernia. No pharmacological studies have been reported yet. Now we will introduce our research in the following: I. Inhibitory effects on the central nervous system 1. Impact on the sleeping time of pentobarbital Alcohol extract aqueous solution 15, 15 and 20g/kg (calculated with the original drug, the same below). The control group was intragastrically injected with equal volume of normal saline and each rat 40’.