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本文采用IFA法对32例慢性乙肝和21例正常健康者的外周血T细胞亚群CD_3、CD_4CD_8进行检测,以探讨慢性乙肝患者肝功能改变、乙肝病毒复制与T细胞亚群的关系。作者认为.CD_4/CD_8比值可作为判断慢性乙肝患者免疫状态、病情变化及预后的指标之一。
In this paper, T cell subsets CD_3 and CD_4CD_8 in peripheral blood of 32 patients with chronic hepatitis B and 21 healthy controls were tested by IFA to explore the relationship between liver function and hepatitis B virus replication and T cell subsets in chronic hepatitis B patients. The authors believe that CD_4 / CD_8 ratio can be used as one of the indicators to judge the immune status, disease status and prognosis of chronic hepatitis B patients.