艾伦脑科学研究所绘制的脑基因图集,不仅仅能够用于区分人和其他动物,还将有助于推进人脑神经以及精神疾病的相关研究工作。人脑的基因究竟是怎么活动的,它们如何分布,多年来一直是一个待解的题目。在科学家们的不断探索下,虽然小鼠的全基因组基因表达的高分辨图已经问世多年,但是人脑的基因分布却并未取得较大进展,仅仅是发表过一些相对比较粗糙的基因分布图。人体和小鼠相比规模大1000多倍,且死后人体组织供应有限以及质量较差等问题都给研究带来了挑战。 The Brain Gene Atlas drawn by the Allen Institute for Brain Science can not only distinguish between humans and other animals, but also contribute to the advancement of studies on human brain and mental disorders. How the human brain’s genes act and how they are distributed have been a subject for many years. Under the continuous exploration of scientists, although the high-resolution genome-wide mouse gene expression has been around for many years, no significant progress has been made in the human brain gene distribution, just published some relatively rough gene profiles . Human and mouse size than 1000 times larger, and the supply of human tissue after death is limited and poor quality and other issues have brought challenges to the study.