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用放射免疫法测定血清GS浓度,胃及十二指肠溃疡患者空腹时GS与正常值无明显差别;在萎缩性胃炎的分型中,GS的变化可以部分反映胃窦粘膜受损程度;而测定血清GS则是检出胃泌素瘤的主要诊断方法。通过胰泌素刺激试验可区别高GS血症是否来自胃泌素瘤;蛋白质试餐可刺激血清GS升高,但针刺足三里穴及针刺非穴位处均不能引起血清GS的明显变化。
Serum GS concentration was measured by radioimmunoassay. There was no significant difference between GS and normal in fasting gastric and duodenal ulcer patients. In the classification of atrophic gastritis, the change of GS could partly reflect the damage degree of antral mucosa; Determination of serum GS is the main diagnosis of gastrinoma. Secretion of glucocorticoid could be used to distinguish whether hyperglycemia came from gastrinoma. Serum GS could be stimulated by protein test, but no significant changes of serum GS could be induced by acupuncture at Zusanli acupoint and acupuncture at non-acupoints.