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目的探讨血清C-反应蛋白浓度在呼吸道病毒感染中的诊断作用与临床治疗意义。方法回顾性分析深圳市南山人民医院于2012年3月至2013年3月收治的181例呼吸道感染患者的临床资料,根据患者所感染的病原体类型将所有患者分为细菌感染组(63例)、病毒感染组(58例)及支原体感染组(60例),并选取同时期于我院进行健康体检的60名健康者作为对照组。比较各组治疗前后血清C-反应蛋白的浓度与白细胞数量。结果细菌感染组、病毒感染组、支原体感染组及对照组血清C-反应蛋白浓度及白细胞计数检测结果比较差异有统计学意义(P<0.05);经过治疗,所有患者的血清C-反应蛋白浓度均明显下降(P<0.05),细菌感染组治疗前后白细胞总数比较差异有统计学意义(P<0.05)。结论 C-反应蛋白浓度的升高对于呼吸道病毒感染的早期诊断有一定的意义,在患者接受治疗后,其浓度还能够反应治疗的临床疗效。
Objective To investigate the diagnostic value and clinical significance of serum C-reactive protein in respiratory virus infection. Methods The clinical data of 181 patients with respiratory tract infection admitted from March 2012 to March 2013 in Shenzhen Nanshan People’s Hospital were retrospectively analyzed. All patients were divided into bacterial infection group (63 cases) according to the type of pathogen infected by the patient, (58 cases) and mycoplasma infection group (60 cases), and 60 healthy people who took physical examination in our hospital at the same time were selected as the control group. The levels of serum C-reactive protein and the number of white blood cells in each group before and after treatment were compared. Results The results of serum C-reactive protein and leukocyte count in bacterial infection group, virus infection group, mycoplasma infection group and control group showed significant difference (P <0.05). After treatment, the serum C-reactive protein (P <0.05). The total number of leukocytes in bacterial infection group before and after treatment was significantly different (P <0.05). Conclusions The elevated C-reactive protein level has certain significance for the early diagnosis of respiratory virus infection. After treatment, the concentration of C-reactive protein can reflect the clinical effect of treatment.