1990年7月1日,我院用同一份O型血浆输注4例小婴儿后,均发生急性溶血反应,其中1例抢救无效死亡。1.临床资料:4例患儿均为男性,年龄8天～6个月。原发病为新生儿肺炎、低钙血症1例,小儿肠炎及维生素D缺乏性手足搐搦症各1例(均伴有营养不良),另1例为乳儿肝炎综合征。4例患儿均因病情重、反应差而输注同一份O型新鲜血浆(40、50ml者各2例)。其中1例输至30ml后,2例输后及1例输后3小时病情急骤变化,先后出现寒战、发热、呼吸困难、面色青灰等;4例分别于 July 1, 1990, our hospital with the same O-plasma infusion of 4 cases of infants, all acute hemolysis occurred, of which 1 died of rescue ineffective. 1. Clinical data: 4 cases of children were men, aged 8 days to 6 months. The primary disease was neonatal pneumonia, hypocalcemia in 1 case, pediatric enteritis and vitamin D-deficient tetany in 1 case (all with malnutrition), and the other was infantile hepatitis syndrome. All 4 patients were infused with the same O-type fresh plasma (2 in each of 50 and 50 ml) due to their serious illness and poor response. Among them, 1 case lost to 30ml, 2 cases lost and 1 case lost 3 hours after the sudden change of condition, chills, fever, dyspnea,