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许多作者报导了药原性心脏副作用如:心律失常,心动过速及其它心电图改变,甚至造成猝死.本文根据1968~1974年美国和芬兰六所精神病院连续观察的1932例住院病人的资料,发现其中34例有心脏副作用.在有心脏病的人中,心脏副作用的发生率较高,心脏副作用的评定是根据入院时有(48例)无(1884例)心脏病为准.其结果如下:有心脏病者48例有心脏病,平均年龄为61岁,其中67%为女性,最通常的主要诊断为抑郁症(50%)和精神分裂症(15%).在此48例中9例(18.8%)有心脏副作
Many authors have reported pharmacological cardiac side effects such as arrhythmia, tachycardia and other electrocardiographic changes, and even sudden death.According to the data of 1932 inpatients continuously observed in six psychiatric hospitals in the United States and Finland from 1968 to 1974, Of these, 34 had heart-related side effects, with a high incidence of heart-related side effects in those with heart disease and heart side effects assessed on the basis of admission (48 cases) without (1884) heart disease.The results are as follows: Forty-eight patients with heart disease had a heart attack, with an average age of 61 years, 67% of whom were women, the most common of the major diagnoses being depression (50%) and schizophrenia (15%). Of the 48 patients, 9 (18.8%) had cardiac side-effects