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充血性心力衰竭（ＣＨＦ）具有复杂的神经内分泌变化，近年发现内源性阿片肽参与ＣＨＦ的发病过程〔１〕。孤啡肽（ＯＦＱ）是阿片肽的一种特殊类型，具有降低痛阈、调节情感及稳定内环境等多种生物学效应〔２〕。本研究测定了ＣＨＦ患者外周血ＯＦＱ水平，旨在探讨ＣＨＦ...
Congestive heart failure (CHF) has a complex neuroendocrine changes in recent years found that endogenous opioid peptide involved in the pathogenesis of CHF 〔1〕. OFQ is a special type of opioid peptide with various biological effects such as reducing pain threshold, regulating emotion and stabilizing internal environment [2]. This study measured the peripheral blood OFQ levels in patients with CHF, designed to explore the CHF ...