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周围性面神经瘫痪(Bell’s瘫)的病因仍不清楚。本研究的目的是通过对患有原因不明的周围性面神经瘫痪的儿童和成年人的血清学和脑脊液的研究,来探讨此病的发病机理。材料和方法研究对象包括7个儿童,年龄2～11岁,5个成年人,年龄24～62岁。对所有病人进行了临床、神经系统和耳神经的检查。对所有成年人和部分儿童进行了电味觉、纯音听力、肌电图及镫骨肌反射测定。全部患者进行了血常规和血沉测定。面瘫开始1周内全部进行了血液和脑脊液的血清学检查、2～4周后作了第2次血液血清学检查,其中9例又进行了脑脊液的血清学检查。标本作了是否含有腮腺炎、麻疹、水痘病毒、腺病毒、巨细胞病素、ECHO病毒、单纯疱疹病毒和EB病毒抗体的分析。血脑屏障机能通过测定脑脊液白蛋白/血清白蛋白比值评
The cause of peripheral facial paralysis (Bell’s paralysis) remains unclear. The purpose of this study was to investigate the pathogenesis of this disease by studying serological and cerebrospinal fluid in children and adults with unexplained peripheral facial paralysis. Materials and Methods Subjects included seven children aged 2 to 11 years and 5 adults aged 24 to 62 years. All patients underwent clinical, neurological and auditory nerve examinations. Taste, pure tone, EMG, and stapedius reflexes were measured on all adults and some children. All patients underwent blood tests and ESR. Serological tests of blood and cerebrospinal fluid were performed in the first week of facial paralysis, and the second blood serological examination was performed after 2 to 4 weeks, of which 9 patients were subjected to serological examination of cerebrospinal fluid. Specimens were analyzed for mumps, measles, varicella, adenovirus, cytomegalovirus, ECHO, herpes simplex and Epstein-Barr virus. Blood-brain barrier function was assessed by measuring cerebrospinal fluid albumin / serum albumin ratio