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当前流行的关于血吸虫成虫如何逃避宿主免疫系统的假设有二个:(1) 获得宿主抗原作为避免表面识别的形式。(2) 依靠表面大分子的强烈转换来避免由于表面组织形成免疫复合体而产生的损害。上述二种机理可假定为表面含糖的分子起着一种重要的作用,以及在表面转换的情况下,血吸虫的糖基转移酶系统也将被包括在内。因此关于血吸虫糖蛋白及糖脂的结构及分布模型以及它们的生物合成机理的详细资料将有助于澄清宿主一寄生虫之间某些重要方面的关系。
There are currently two popular hypotheses about how Schistosoma adults evade the host’s immune system: (1) Host antigens are obtained as a form that avoids surface recognition. (2) rely on the strong conversion of surface macromolecules to avoid the damage caused by surface tissue forming immune complexes. The above two mechanisms can be assumed to play an important role as surface-sweetened molecules, and the Schistosoma glycosyltransferase system will also be included in the case of surface conversion. Therefore, detailed information on the structure and distribution models of Schistosoma glycoproteins and glycolipids and their biosynthetic machinery will help clarify some important aspects of host-parasite relationships.