新近研究发现:在人的增生性肾小球肾炎和动物的实验性肾小球肾炎模型中,巨噬细胞起着重要作用。造成动物缺乏巨噬细胞的实验能防止肾小球内巨噬细胞浸润及肾小球病变的发生,说明了这些细胞在介导肾小球损伤方面的作用,但其渗出及堆积的机制仍不清楚。许多重要的生物现象,包括补体激活,免疫粘连是IgG分子经由Fc受体激发的。巨噬细胞膜上 Recent studies have found that macrophages play an important role in human models of proliferative glomerulonephritis and experimental glomerulonephritis in animals. Experiments that resulted in the lack of macrophages in animals prevented the infiltration of glomerular macrophages and the occurrence of glomerular lesions, suggesting the role of these cells in mediating glomerular injury but the mechanism of their exudation and accumulation Not clear. Many important biological phenomena, including complement activation, are the activation of IgG molecules via Fc receptors. Macrophage membrane