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用聚合酶链反应(PCR)检测了45例肺科病人的支气管肺泡灌洗液(BALF)中乙肝病毒(HBV),同时对其中24例作血清HBV检测,发现BALF中HBV阳性率为26.67%(12/45)、血清HBV阳性率为41.67%(10/24);血清HBV阳性者其BALF方有可能检出HBV、血清HBV阴性者其BALF不能检出HBV,BALF中HBV脱氧核糖核酸(HBV-DNA)可以复制、有传染性。
A total of 45 cases of bronchial alveolar lavage fluid (BALF) in patients with pulmonary disease were detected by polymerase chain reaction (PCR) and HBV was detected in 24 of them. The positive rate of HBV in BALF was 26. 67% (12/45). The positive rate of serum HBV was 41.67% (10/24). The serum of patients with positive HBV was likely to be detected in BALF. HBV in BALF was not detected in patients with negative serum HBV. Deoxyribonucleic acid (HBV-DNA) can replicate and be contagious.