单纯疱疹性角膜炎是难治的角膜病之一。随着抗生素和激素的广泛应用单纯疱疹性角膜炎的发病率呈上升趋势。我科于1991年7月至1992年7月应用西咪替丁球结膜下注射及滴眼,共治疗19例单纯疱疹性角膜炎患者,取得了满意效果,报告如下。19例患者中男12例,13眼,浅层型7例,7眼,深层型5例6眼,女7例,8眼、浅层型6例,6眼,深层型1例,2眼。最小年龄10岁,最大年龄59岁,平均年龄43岁。发病时间最短3天,最长90天,平均发病天数为18天。初发者10例,复发者9例。19例患者均为门诊病例。治疗前均有明显的发病诱因,如发热、感冒、上呼吸道感染、劳累、情绪不稳定等。眼部症状有睫状充血或混合性充血,有角膜刺激征,角膜知觉迟钝,角膜有树枝状、地图状、盘状、点片状浸润。角膜后有kp,荧光素染色阳性。治疗期间停用其他抗病毒药物,只用上海第一 Herpes simplex keratitis is refractory to one of the corneal diseases. With the widespread use of antibiotics and hormones, the incidence of herpes simplex keratitis is on the rise. My department in July 1991 to July 1992 application of cimetidine subconjunctival injection and eye drops, a total of 19 patients with herpes simplex keratitis, and achieved satisfactory results, the report is as follows. Among the 19 patients, there were 12 males and 13 females, 7 superficial femurs and 7 superficial femurs. There were 6 males and 6 females, 7 females, 8 females, 6 superficial femurs, 6 superficial femurs and 1 deep mucosa. . The youngest is 10 years old, the oldest is 59 years old and the average is 43 years old. The shortest onset time of 3 days, the longest 90 days, the average number of days of onset was 18 days. Initial onset in 10 cases, recurrence in 9 cases. All 19 patients were outpatients. Before treatment there are obvious incentives, such as fever, cold, upper respiratory tract infection, exertion, emotional instability and so on. Ocular symptoms of ciliary congestion or mixed congestion, corneal irritation, corneal sensitivity, dendritic cornea, map-like, disk-shaped, punctate infiltration. Corneal kp, fluorescein staining positive. Disable other antiviral drugs during treatment, only Shanghai first