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目的观察中西药联合治疗对冠心病患者血浆脑钠肽(BNP)水平变化的影响。方法选取医院2014年1月-2015年12月收治的冠心病患者50例,将其随机分为治疗组和对照组各25例。对照组采用西药进行治疗,治疗组在西医治疗的基础上联合中药进行治疗,临床对比分析2组患者治疗前后的血浆BNP水平变化。结果治疗前2组血浆BNP水平比较差异无统计学意义(P>0.05),治疗后治疗组血浆BNP水平为(462.77±142.18)μg/L明显低于对照组的(1034.04±325.06)μg/L,差异有统计学意义(P<0.05)。结论中西药联合治疗方式对冠心病患者有很好的应用效果,疗效更加显著,能够有效的改善患者的血浆BNP水平,值得临床推广应用。
Objective To observe the effect of combination therapy of Chinese and western medicine on the plasma level of brain natriuretic peptide (BNP) in patients with coronary heart disease. Methods Fifty patients with coronary heart disease admitted in our hospital from January 2014 to December 2015 were randomly divided into treatment group (25 cases) and control group (25 cases). The control group was treated with western medicine. The treatment group was treated with traditional Chinese medicine on the basis of western medicine treatment. The changes of plasma BNP levels in two groups before and after treatment were analyzed clinically. Results There was no significant difference in plasma BNP level between the two groups before treatment (P> 0.05). After treatment, plasma BNP level in the treatment group was significantly lower than that in the control group (462.77 ± 142.18 μg / L vs (1034.04 ± 325.06 μg / L , The difference was statistically significant (P <0.05). Conclusion The combination of Chinese and Western medicine has a good effect on patients with coronary heart disease, the effect is more significant, can effectively improve the plasma BNP levels in patients, it is worthy of clinical promotion and application.