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目的分析随州市发热伴血小板减少综合征(SFTS)的流行特征,探讨可能的传播途径,为SFTS防控提供科学依据。方法采用描述流行病学对2010年-2012年监测数据进行分析,对病例进行个案调查和病原学检测分析;选择有确诊病例的村进行传播媒介蜱密度调查和家畜总抗体水平调查及蜱的检测。结果随州市2010年-2012年共报告发热伴血小板减少综合征病例205例,其中确诊病例73例,死亡15例;呈散发状态,发病高峰在5月-7月;发病年龄为38岁~86岁(M=59岁);农民占98.63%,发病病例与蜱密度季节消长呈正相关。采集的91例住院病例新布尼亚病毒(SFTSV)核酸阳性率为54.94%;健康人的总抗体阳性率为3.82%;病例家宿主动物总抗体阳性率为63.15%,羊蜱的SFTSV核酸阳性率为17.65%。结论随州市为SFTS高发地区,发病主要在春夏季。提示重点防护人群为农民,蜱可能是传播媒介,做好宣传防护。
Objective To analyze the epidemiological characteristics of fever with thrombocytopenia syndrome (SFTS) in Suizhou and to explore possible routes of transmission to provide a scientific basis for prevention and control of SFTS. Methods Descriptive epidemiology was used to analyze surveillance data from 2010 to 2012, case studies and etiological analysis were conducted. Selected villages with confirmed cases were surveyed for tick density and total antibody levels and ticks . Results A total of 205 cases of fever with thrombocytopenia syndrome were reported in Suizhou from 2010 to 2012, of which 73 cases were diagnosed and 15 died. The disease was sporadic and peaked at May to July. The age of onset was 38 years to 86 years Year old (M = 59); peasants accounted for 98.63%, the incidence of cases and the seasonal fluctuation of tick density was positively correlated. The positive rate of SFTSV nucleic acid in 91 inpatients was 54.94%. The positive rate of total antibody in healthy volunteers was 3.82%. The positive rate of SFTSV nucleic acid in goat was 63.15% The rate was 17.65%. Conclusion Suizhou is a high incidence of SFTS, the incidence is mainly in the spring and summer. Tip focus on the protection of peasants, ticks may be the media, good propaganda and protection.