氨硫脲(TB_1)目前在抗结核治疗中占有一定地位,被国内外公认为大范围防痨工作中基本治疗方案的四个主要药物之一。但此药副作用较多,因皮肤粘膜出现不良反应而被迫停药者为数不少,有的甚至引起严重后果。为探索对副作用的治疗,我们用口服黄连素治疗TB_1引起的皮肤粘膜副作用二例,均获满意效果,现报告如下: 例1 男,19岁,病案号:33819。因肺结核于1983年1月19日入院.痰菌阳性。用INH、SM、PAS治疗,二个月后因PAS引起不良反应而停用,改服 Thiourea (TB_1) is currently in the anti-TB treatment occupies a certain position, at home and abroad is recognized as a large-scale anti-tuberculosis work in the basic treatment of one of the four major drugs. However, the side effects of this drug are more due to skin and mucous membranes adverse reactions were forced to stop a large number of patients, and some even caused serious consequences. To explore the side effects of treatment, we use oral berberine treatment of TB1-induced skin and mucous membrane side effects in two cases were satisfactory results are as follows: A male, 19 years old, the case number: 33819. Tuberculosis was admitted to hospital on January 19, 1983. Positive sputum bacteria. With INH, SM, PAS treatment, two months later due to adverse reactions caused by PAS disable, change clothes