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选择氟暴露工龄５年以上的男性工人４０名，随机分为Ａ、Ｂ两组，每组２０人，Ａ组为服药组，Ｂ组为非服药组；另选非氟暴露工人１５名为阴性对照组（Ｃ组），观察“抗氟灵”抗氟损伤效果。结果表明，氟暴露工人外周血ＡＫＰ、ＧＳＨ－ＰＸ活性、尿Ｆ－、ＢＦ４－含量明显高于非氟暴露组工人，而血清ＳＯＤ活性则相反。服药后，Ａ组以上各指标除ＧＳＨ－ＰＸ变化不显著外，其它指标均有显著性改变，其中血清ＡＫＰ活性和尿Ｆ－含量降低，且明显低于Ｂ组；血清ＳＯＤ活性和尿ＢＦ４－含量显著升高，且明显高于Ｂ组。揭示“抗氟灵”对氟损伤的拮抗有一定效果。
40 male workers who were exposed to fluoride exposure for more than 5 years were randomly divided into A and B groups of 20 patients in each group. Group A received medication and group B received non-medication. Fifteen non-fluoride exposed workers were negative Control group (C group), observed “anti-fluoride Ling” anti-fluoride effect. The results showed that AKP, GSH-PX activity, urinary F- and BF4- in peripheral blood of workers exposed to fluoride were significantly higher than those in non-fluoride exposed workers, while serum SOD activity was opposite. After taking the medicine, except for the changes of GSH-PX in group A, the other indexes all had significant changes, the serum AKP activity and urinary F-content decreased, and were obviously lower than those in group B. Serum SOD activity and urine BF4- Content was significantly increased, and significantly higher than the B group. Reveal “Fluorine resistance” on the fluorine antagonism has some effect.